International Journal of Genetics and Genomics

Volume 10, Issue 4, December 2022

  • Vaccine Design for Marburg Virus Using VP35 Protein

    Mohammed Yousif Mohammed, Mona Abdelrhman Mohamed Khaier, Nuha Agabna, Sania Shaddad

    Issue: Volume 10, Issue 4, December 2022
    Pages: 85-93
    Received: Oct. 22, 2022
    Accepted: Dec. 08, 2022
    Published: Dec. 28, 2022
    DOI: 10.11648/j.ijgg.20221004.11
    Abstract: Background: Marburg virus is cause hemorrhagic fever for human, and transmits by exposure to one species of fruit bats, and transmits from person to person by body fluid it cause fever and bleeding but not like Ebola virus symptoms. Aim: in this study use bioinformatics tools to design a vaccine using vp35 protein which is part of virus cell that c... Show More
  • The Effect of Non-synonymous Single Nucleotide Polymorphisms Variants in ALPL Gene, a Computational Approach

    Nabaa Kamal Alshafei, Intisar Hassan Saeed, Mona Abdelrahman Mohamed Khaier

    Issue: Volume 10, Issue 4, December 2022
    Pages: 94-102
    Received: Jul. 06, 2022
    Accepted: Sep. 26, 2022
    Published: Dec. 29, 2022
    DOI: 10.11648/j.ijgg.20221004.12
    Abstract: Background: Phosphorus is one of the major macronutrient essential for normal growth and development of living organisms. Alkaline phosphatase (ALP) is an enzyme present in human and animals responsible for solubilization and mineralization of organic phosphate and makes it readily available for the body. The disease Hypophosphatasia (HPP) is an au... Show More