International Journal of Genetics and Genomics

Volume 4, Issue 4, August 2016

  • CTLA-4 Gene Polymorphism in Women with Idiopathic Recurrent Pregnancy Loss

    Eman N. Helles, Mohammed J. Ashour, Fadel A. Sharif

    Issue: Volume 4, Issue 4, August 2016
    Pages: 31-35
    Received: Aug. 08, 2016
    Accepted: Aug. 17, 2016
    Published: Sep. 05, 2016
    Abstract: Cytotoxic T lymphocyte associated antigen-4 (CTLA-4) is considered as a negative regulator of T cell activation and its role in maintaining immune tolerance is well established. The present case-control study aimed to investigate the CTLA-4 +49 A/G, -1661 A/G, -318 C/T and -1722 T/C single nucleotide polymorphisms (SNPs) and predisposition to recur... Show More
  • Virulence Factors of E. coli ST131 and Its H30 and H30Rx Subclones Among Extended-Spectrum Beta-Lactamase Producing Isolates

    Khadega Yahya Abdullah AL-hetar, Nanjaiah Lakshmidevi

    Issue: Volume 4, Issue 4, August 2016
    Pages: 36-39
    Received: Aug. 17, 2016
    Accepted: Aug. 26, 2016
    Published: Sep. 18, 2016
    Abstract: Escherichia coli sequence type 131 (ST131) is a pandemic clone causing predominantly community and hospital-onset antimicrobial-resistant infections. Recently, H30-Rx subclone of E. coli has been disseminated among ST131 strains in combination with beta lactamase subtype CTX-15that may play a role in the prevalence of antibiotic resistance among E.... Show More