International Journal of Genetics and Genomics

Volume 8, Issue 4, December 2020

  • Pathosystem, Epiphytology and Genomic Characterization of Groundnut Rosette Disease Pathogens

    Anthony Simiyu Mabele, Mariam Nyongesa Were

    Issue: Volume 8, Issue 4, December 2020
    Pages: 120-126
    Received: Sep. 27, 2020
    Accepted: Oct. 12, 2020
    Published: Oct. 16, 2020
    Abstract: Synergism among the groundnut rosette disease (GRD) pathogens of Groundnut rosette assistor virus (GRAV, Luteovirus) and Groundnut rosette virus (GRV, Umbravirus) associated with a satellite-ribonucleic acid (sat-RNA), have declined groundnut (Peanut, Arachis hypogaea L.) production in Kenya. The polyphagous groundnut aphid (Aphis craccivora Koch;... Show More
  • Medium-Chain Acyl-CoA Dehydrogenase Deficiency (MCADD): A Case of Recurrent Vomiting and Diarrhea

    Dian Sulistya Ekaputri, I. Gusti Lanang Sidiartha, I. Gusti Ayu Putu Eka Pratiwi

    Issue: Volume 8, Issue 4, December 2020
    Pages: 127-132
    Received: Sep. 26, 2020
    Accepted: Oct. 10, 2020
    Published: Oct. 20, 2020
    Abstract: Medium chain acyl-CoA dehydrogenase deficiency (MCADD) is the commonest fatty acid oxidation disorder. Patients usually presented between the ages of 4 months and 4 years with acute hypoglycaemic encephalopathy and liver dysfunction; some deteriorated rapidly and died. Symptomatic presentation of MCADD is precipitated by fasting due to infection, c... Show More
  • Gaucher Disease: A Rare Case in Children with Malignancy-Like Manifestation

    I Made Karma Setiyawan, I Gusti Lanang Sidiartha, I Gusti Ayu Putu Eka Pratiwi

    Issue: Volume 8, Issue 4, December 2020
    Pages: 133-137
    Received: Oct. 15, 2020
    Accepted: Oct. 26, 2020
    Published: Nov. 04, 2020
    Abstract: Gaucher Disease (GD) is an autosomal recessive systemic lysosomal storage disorder which is characterized by glucocerebroside deposition in cells of the macrophage-monocyte system as a result of a deficiency in lysosomal glycosidase (glucocerebrosidase). The high prevalence of symptomatic hepatosplenomegaly and thrombocytopenia in GD commonly lead ... Show More
  • ACTN3 R577X Polymorphism Impacts Glucose Consumption at Simulated High Altitude

    Ricardo Muller Bottura, Giscard Humberto Oliveira Lima, Debora Cristina Hipolide, Joao Bosco Pesquero

    Issue: Volume 8, Issue 4, December 2020
    Pages: 138-142
    Received: Oct. 26, 2020
    Accepted: Nov. 10, 2020
    Published: Nov. 23, 2020
    Abstract: Introduction: High altitude acclimatization is a process that involve several physiological adjustments, which may increase glucose metabolism because of acute hypoxic exposure. Native highlanders like Tibetans show an increased anaerobic glucose metabolism and a higher proportion of type I muscle fiber than lowlanders. Actin filaments are anchored... Show More