International Journal of Genetics and Genomics

Volume 4, Issue 6, December 2016

  • Genetic Assessment of the Shrub Syncepalum dulcificum (SCHUMACH & THONN.) Daniell in Nigeria Using the Randomly Amplified Polymorphic DNA (RAPD)

    Iloh Andrew Chibuzor, Orosun Bukola, Akinyele Olukemi Adejoke, Onyenekwe Paul Chidozie

    Issue: Volume 4, Issue 6, December 2016
    Pages: 45-50
    Received: Dec. 27, 2016
    Accepted: Jan. 07, 2017
    Published: Jan. 24, 2017
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    Abstract: In order to advocate for informed management decisions with regards to endangered species, we assessed genetic diversity and genetic structure in 40 individuals of six natural populations of the shrub Syncepalum dulcificum (SCHUMACH & THONN.) DANIELL growing in South Western Nigeria. Twelve (12) Random Amplified Polymorphic DNA (RAPD) primers were ... Show More
  • Future Medicine such as Gene or Stem Cell Therapy Are Better Than Non biological or Some Biological (Antibiotic)

    Ikram Hasan

    Issue: Volume 4, Issue 6, December 2016
    Pages: 51-54
    Received: Sep. 17, 2016
    Accepted: Oct. 19, 2016
    Published: Jan. 25, 2017
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    Abstract: At present all the drug both some biological (only antibiotic or antimicrobial agent) and Non biological drug gradually decrease their efficacy. Biological drugs such as antimicrobial agents, antibiotics are gradually resistance by microorganism. After 20 to 40 years later 60 to 90 percent antibiotics or antimicrobial agents will be resistance by m... Show More
  • Fetal Stem Cells Use in Complex Treatment of Patients with Acquired Aplastic Anemia and Therapy Effect on Recovery of Hematopoietic Functions

    Mikhail M. Shulak, Mariya O. Klunnyk, Iryna G. Matiyashchuk, Olena V. Ivankova, Marina V. Skalozub, Nataliia S. Sych, Mariya P. Demchuk, Andriy A. Sinelnyk, Timur V. Karayev, Khrystyna I. Sorochynska

    Issue: Volume 4, Issue 6, December 2016
    Pages: 55-60
    Received: Jan. 25, 2017
    Accepted: Feb. 20, 2017
    Published: Mar. 21, 2017
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    Abstract: The principal objective was studying effects of complex treatment using fetal stem cells (FSCs) on recovery of hematopoietic function. 50 patients suffering from aplastic anemia of different disease severity were under study and underwent complex treatment by use of cryopreserved suspensions containing fetal liver cells extracted from 7-12 week ges... Show More
  • Immunobiology of Dental Tissue-Derived Stem Cells; As a Potentiated Candidate for Cell Therapy

    Abdolreza Esmaeilzadeh, Elahe Reyhani, Nazila Bahmaie

    Issue: Volume 4, Issue 6, December 2016
    Pages: 61-67
    Received: Mar. 01, 2016
    Accepted: Mar. 22, 2016
    Published: Mar. 22, 2017
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    Abstract: Background and aims: Mesenchymal stem cells (MSCs) are non-hematopoietic, undifferentiated, heterogeneous and multipotential stem cells population with immunosuppressive capacities in innate and acquired immune systems. During last decade, they have glisten in regenerative medicine. They can differentiate into various cell types and secrete soluble... Show More
  • The Insertion Timing of PEGylated Lipids to Galactosylated Lipoplexes Is Important for Liver-Selective Transfection in Mice

    Shintaro Fumoto, Naoki Taniguchi, Yuri Ikai, Naoki Yoshikawa, Hirotaka Miyamoto, Hitoshi Sasaki, Mitsuru Hashida, Shigeru Kawakami, Koyo Nishida

    Issue: Volume 4, Issue 6, December 2016
    Pages: 68-78
    Received: Mar. 10, 2016
    Accepted: Mar. 22, 2016
    Published: Mar. 22, 2017
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    Abstract: In the present study, we demonstrated the importance of PEGylation timing of galactosylated liposome/plasmid DNA (pDNA) complexes (lipoplexes) for liver-selective transfection in mice. Because a fenestrated endothelium can be a barrier for penetration of lipoplexes though sinusoids, the particle size of lipoplexes is one of the determining factors ... Show More
  • Transplantation of Embryonic Ventral Mesencephalic Tissue in 6-OHDA Induced Parkinsonism Rat Brain for Cell Based Therapy: A Perspective of Methods

    Biswarup Ghosh, Angelo Lepore, George Smith

    Issue: Volume 4, Issue 6, December 2016
    Pages: 79-84
    Received: Jul. 18, 2016
    Accepted: Jul. 29, 2016
    Published: Mar. 22, 2017
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    Abstract: Parkinson’s disease (PD) is characterized as a disease of the basal ganglia, with a progressive degeneration of dopaminergic neurons located in the substantia nigra (SN) and projecting to the striatum with subsequently loss of the nigrostriatal circuit. The potential for therapeutic use of cell transplantation for cell replacement has received a gr... Show More